Inhibiting Hsp90 chaperone roles using 17AAG induces cytostasis or apoptosis in tumor cells through destabilization of several mutated cancer promoting proteins.Although mitochondria are central in deciding the fate of cells, 17AAG induced effects on tumor cell mitochondria were largely unknown.Here, we show that Hsp90 inhibition with 17AAG first a
We report a 46-year-old male patient with retinocytoma who presented at the age of 31 asymptomatically.An intraocular retinal mass was incidentally found in his right eye, when he underwent ophthalmological assessment for refractive surgery.This tumor consisted of a calcified sessile basis partially covered by a pedunculated salmon-pink growth.Init
The purpose of the study was to determine whether consumer loyalty mediates between service quality and consumer commitment in the beauty salon industry.It was also to determine whether these relationships difference between beauty salon in shopping centers and beauty salon in community residences.A theoretical framework was developed to test the p
Introduction: Multimorbidity is increasingly recognized as a key issue in the prevention and management of chronic diseases.We examined the prevalence and correlates of chronic disease multimorbidity in the general adult Canadian population in relation to age and other key determinants.Methods: We extracted data MOST25 Pre-Amp from the Canadian Com
The terminal-connected series dynamic braking resistor (SDBR) is applied to assist the low-voltage ride-through Cutting Board Mats (LVRT) of the doubly-fed induction generator (DFIG).With the fault current and switch-in of the SDBR, the stator voltage oscillates, thus the constant stator voltage drop assumption is invalid and the effect of the conv